Many runners describe a euphoric feeling during or after a run known as a “runner’s high.” This article explores the science behind that sensation, explaining how exercise triggers natural chemicals in the body that improve mood, reduce anxiety, and even decrease pain perception. Experts say the effect is largely driven by the body’s endocannabinoid system, which can be activated through sustained aerobic exercise like running.
The Science Behind a Runner’s High
Mar 10, 2026 | Athletic Performance, Orthobiologics, Physical Therapy, Sports Medicine